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A quintessential Southern classic, this grilled cheese is elevated with a creamy, tangy, and slightly spicy homemade pimento cheese spread, melted to gooey perfection between two slices of buttery, golden-brown bread. It's the ultimate comfort food, ready in just 20 minutes.
Prepare the Pimento Cheese Spread
Assemble the Sandwiches
Grill the Sandwiches

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A quintessential Southern classic, this grilled cheese is elevated with a creamy, tangy, and slightly spicy homemade pimento cheese spread, melted to gooey perfection between two slices of buttery, golden-brown bread. It's the ultimate comfort food, ready in just 20 minutes.
This southern recipe takes 20 minutes to prepare and yields 4 servings. At 841.8 calories per serving with 24.16g of protein, it's a beginner-friendly recipe perfect for lunch or dinner or snack.
Serve
Add finely diced fresh jalapeños or a dash of your favorite hot sauce to the pimento cheese mixture for extra heat.
Layer a few slices of crispy cooked bacon or a slice of country ham inside the sandwich before grilling.
Incorporate other cheeses like Monterey Jack, Colby, or a bit of smoked Gouda along with the cheddar for a more complex flavor profile.
Mix in some freshly chopped chives or green onions into the pimento cheese spread for a fresh, oniony bite.
The cheddar and cream cheese provide a significant amount of calcium, which is essential for strong bones and teeth, as well as proper nerve and muscle function.
Cheese is a good source of high-quality protein, which is crucial for building and repairing tissues, making enzymes and hormones, and supporting muscle mass.
The carbohydrates from the bread provide a quick source of energy for your body and brain, making this a satisfying and fueling meal.
Pimentos are a type of red pepper rich in Vitamin A, an antioxidant that supports vision, immune function, and cell growth.
A single Pimento Grilled Cheese sandwich contains approximately 650-750 calories, depending on the specific type of bread, cheese, and mayonnaise used.
Pimento Grilled Cheese is a rich and indulgent comfort food. It is high in calories, saturated fat, and sodium. While delicious as an occasional treat, it is not considered a health food. You can make it slightly healthier by using whole-wheat bread and a reduced-fat cheese.
Absolutely! The pimento cheese spread is perfect for making ahead. It can be stored in an airtight container in the refrigerator for up to one week. The flavors will meld and often taste even better the next day.
A sturdy, thick-sliced bread is ideal. Sourdough, Texas toast, or a thick-cut brioche are excellent choices as they hold up well to the rich filling and create a fantastic crispy crust.
Your heat is likely too high. The key to a perfect grilled cheese is cooking it low and slow. Use medium-low heat to allow the bread to toast gradually, giving the cheese inside enough time to melt completely.
Yes, feel free to customize it! Crispy bacon, pickled jalapeños, or chopped green onions are popular and delicious additions to the cheese spread.